Cereal Grain Proteins

Some Topics

Introduction to Celiac Disease, Gluten Allergy

The prevalence of celiac disease in the general population was believed to be 1 in 300, but recent evidence suggests that there are more undiagnosed than diagnosed cases. A revised estimate of the prevalence in the general population may be greater than 1%. The prevalence of CD among first-degree relatives of people who are diagnosed with CD is as high as 15%. In families with sibling pairs affected by CD, the prevalence of CD is 21.3% in siblings, 14.7% in offspring, 17.2% in first-degree relatives, 19.5% in second-degree relatives, and 17.8% in all relatives.

Immune responses to gluten, the proteins found in cereal grains are a common cause of disease. The gastrointestinal tract is the primary target organ; however systemic disease is an important consequence of cereal grain ingestion in many patients. We think that the people diagnosed with celiac disease are a sub-population of a much larger group with gluten allergy. Latent disease may manifest as irritable bowel syndrome, sometimes with iron deficiency anemia, but little or no diarrhea. Celiac disease is associated with a variety of autoimmune disorders, carcinomas of the gastrointestinal tract and lymphomas.

Gluten-sensitive patients have not been diagnosed.

The prevalence of all forms of gluten allergy may be closer to 20% in a symptomatic population. Most gluten-sensitive patients have not been diagnosed. We argue that any person with celiac-like symptoms, gastrointestinal symptoms, and/or autoimmune disease should do diet revision right away and not worry about an exact diagnosis.

Catassi et al suggested: Many cases of celiac disease are currently undiagnosed. We carried out a pilot study on screening for celiac disease in a school population. The ratio of known to undiagnosed cases was 1 to 6.4. This high prevalence of undiagnosed celiac disease raises a number of problems that require further evaluation. Corazza and Gasbarrini suggested: Since it has been demonstrated that a strict gluten-free diet is protective against the complications of adult celiac disease, it is important that even subclinical and silent forms are diagnosed and treated as early as possible."

Ciacci et al suggested that celiac disease may present in various forms. Their study showed that the disease is more frequent in women, more severe and develops more rapidly. They stated: "The data also suggest the need to look for celiac disease in patients with unexplained anemia. Except for asthenia, all signs and symptoms were more frequent in women than in men. Anemia was the commonest finding in women and was 40% more frequent in women than in men. Dyspepsia was twice as frequent in women as in men. Genital disorders were reported by 44% of women and by no men. Recent weight loss or low body mass index was the commonest finding in men. About 60% of men and women reported diarrhea; among patients without diarrhea, the prevalence of anemia differed between sexes, occurring in about 80% of women."

Biopsy Not Required

Our argument is that gluten-caused disease and the diagnosis of gluten allergy should not depend on intestinal biopsy. The biopsy reveals only one pathological manifestation of gluten allergy. We recommend gluten elimination in all digestive tract disorders and in all the conditions that a commonly related to celiac disease. Our theory is that gluten proteins produce a number of diseases that overlap and are only occasionally manifest as well-defined, discrete disorders.

The diagnosis of celiac disease is, therefore, an arbitrary separation of one small subgroup within a much larger group that suffers disease when they eat gluten. Our assumption is that if you look at symptomatic populations with gastrointestinal symptoms and/or autoimmune disease, then the incidence of gluten sensitivity will be higher than expected. Since a strict gluten-free diet is protective against the consequences of gluten allergy, it is important that undiagnosed forms of celiac disease and non-celiac "gluten allergy" are treated with diet revision.

Troncone et al * stated: "Gluten-sensitive enteropathy is induced by dietary wheat gliadin and related proteins in genetically susceptible individuals. Most evidence suggests an immunologically mediated injury triggered by gluten … it is now becoming clear that a greater proportion of individuals has clinically silent disease, and probably many others have a minor form of the enteropathy. In most countries, the clinical presentation has changed over the past few years coming closer to the adult type of the disease, and the age of onset of symptoms is shifting upward.

Recommendations: The Alpha Nutrition Program is gluten-free and is recommended as the diet revision strategy for anyone with diagnosed celiac disease, or any person with symptoms suggestive of gluten allergy. The diet revision program is explained in enough detail in the Alpha Nutrition Program Manual that an intelligent, well-motivated person can follow the steps outlined. You can order the manual and the Book of Celiac togetherin the starter pack. Alpha Nutrient Formulas are gluten free. Please note that maltodextrin, used in Alpha ENF and Alpha PMX, does not contain gluten and is not related to barley-derived malt. Learn more About Gluten Rescue Starter Pack

Hear About Celiac Disease and Gluten Allergy Prevalence

  • The book, Gluten Problems and Solutions provides both an introduction and also advanced explanations of the immunological basis of gluten induced diseases. The Alpha Nutrition Program is designed to solve the heath problems related to gluten which we consider to be both common and serious. The author is Stephen Gislason MD.

    Download eBook 

    Gluten Free: The exclusion of wheat, rye, barley are the initial steps when gluten allergy is suspected. Gluten elimination should be part of a more comprehensive diet revision plan, preferably in the form outlined in the Alpha Nutrition Program. The Program is gluten-free and is recommended as the best diet revision strategy for anyone with diagnosed celiac disease, or any person with symptoms suggestive of gluten allergy. Learn more about the Alpha Nutrition ProgramGluten free recipes are found in the book, Cooking and Recipes.

    A good way to start your recovery is to Order a Gluten Rescue Starter Pack which includes 2 books and Alpha ENF. If you are not ready for the starter pack, order books and formulas separately.

    Order Starter Pack

  • Order Alpha Education Books

    Alpha Education Books: The books in this series address important health issues and their solution. Everyone, who is interested in Nutritional Therapy, will need a copy of the Alpha Nutrition Program. All books can be downloaded as PDF files.

    Click the add to cart buttons to begin your order for printed books for mail delivery to the USA and Canada. Click the Download buttons to order eBooks for download.

    Print Books Read Topics Download
    Alpha Nutrition Program
    Aching and Fatigue
    Air and Breathing
    Alpha Cooking
    Alcohol Problems
    Gluten Problems
    Diabetes 2
    Eating & Weight
    Skin Disease
    Feeding Children
    Human Brain
    Food Allergy
    Food & Digestion
    Food Choices
    Heart & Arterial
    Immunology Notes
    Inflammatory Arthritis
    Nutrition Notes
    alpha online

    Alpha Nutrition is a trademark and a division of Environmed Research Inc. Environmed was founded in 1984 at Vancouver, BC, Canada Online Since 1995. Experts in Self-Managed Care. Experts in Elemental Nutrient Formulas. All Alpha Nutrition formulas, printed books and Starter packs are ordered online. We ship through the Post Office to all destinations in Canada, and USA. Prices are in Canadian dollars.

    US $ prices are lower, depending on the daily dollar exchange rate.

    Persona Digital publishes a series of books on current topics in psychology, sociology, neuroscience and philosophy. Printed books and eBooks are ordered from Alpha Online. Physical shipments are only to Canada and the USA by postal services. Downloaded eBooks can be delivered to buyers in many countries who use Pay Pal for payments.