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Topics from the Book of Brain
Author
Stephen Gislason MD
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Over half of all diseases are self-inflicted. Negative food effects on brain function are often ignored in neurology and psychiatry. Major diseases originate from eating too much of the wrong food and damage is done to many organs simultaneously. The food supply causes daily brain dysfunction, contributing to mental illness and  neurological diseases. We suggest that a prudent person suffering early brain-dysfunction symptoms would be wise to pursue vigorous, thorough diet revision at the earliest opportunity.  Drugs bought on the street and in pharmacies that target the brain are used excessively and inappropriately adding to  increasing numbers of disturbed and dysfunctional people.

Chantix (Varenicline) Warning

Reports of Suicidal Thoughts, Aggressive Behavior

US Food and Drug Administration (FDA) has informed healthcare professionals about reports of suicidal thoughts as well as some aggressive and erratic behavior in patients who have taken varenicline (Chantix, Pfizer), a smoking-cessation product.  Problems reported were new-onset depressed mood, suicidal ideation, and changes in emotion and behavior within days to weeks of initiating treatment with varenicline,

In one highly publicized case, the FDA notes, erratic behavior led to the death of a patient using varenicline to quit smoking. There are additional reports of patients experiencing drowsiness that affected their ability to drive or operate machinery, the FDA alert notes.

Susan Jeffrey. Medscape Medical News Nov 20 2007. The complete MedWatch safety summary, including a link to the FDA Early Communication Sheet about the ongoing safety review on this issue, can be found at  http://www.fda.gov/medwatch/safety/2007/safety07.htm#Chantix.

The developers of this drug stated: "We have pursued alpha4 beta2 nicotinic receptor partial agonists to inhibit dopaminergic activation produced by smoking while simultaneously providing relief from the craving and withdrawal syndrome that accompanies cessation attempts. Varenicline displays high alpha4 beta2 nAChR affinity and the desired dopaminergic profile."

The problem with this apparently good idea is that this drug acts on core structures in the brain that control emotions, regulate behavior and interface body control with cognitive centers.  Stimulation of nicotinic receptors in the brain, particularly alpha4 beta2 receptors, releases dopamine in the meso-limbic area of the brain. If you are going to add this chemical to the bad mix of chemicals that the patient is already consuming, watch out. Some bad things are going to happen.

Yes, smoking cessation has major health benefits for men and women of all ages and smokers are addicted to nicotine.

The solution is really easy. Just stop smoking.

Several drugs have been prescribed to smokers; it is a potpourri of  different chemicals: bupropion, nortriptyline, clonidine and nicotine patch, gum, inhaler, lozenge and nasal spray. 80% of users of these drugs return to smoking within the first year.

Like all addictions, smoking thrives in groups that accept the habit and disappears in groups that reject the habit.

All Alpha Online nutrient formulas, books and starter packs are ordered online. Alpha Online ships through the Post Office to all destinations in Canada, Continental USA, Alaska, Hawaii, Puerto Rico, and US Military. Prices are listed in Canadian dollars. Alpha Nutrition ® is a registered trademark and a division of  Environmed Research Inc., Sechelt, British Columbia, Canada. In business since 1984. Online since 1995. Persona Publications is also a division of Environmed with a separate online site dedicated to downloading eBooks, other digital documents, and multimedia.

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