heart

Arterial Disease


Heart Attacks



Strokes

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  • Inflammation in Vascular Disease

    The mechanisms of arterial disease appear to be multiple. Hollander of Boston University suggested that atherosclerosis was an autoimmune disorder with immune complexes injuring blood vessel walls. We think that circulating immune complexes often contain food proteins as antigens and this mechanism is important in causing a wide spectrum of food allergic disease. Since proteins derived from meat, milk, eggs and wheat have the highest risk of appearing in the blood as immune complexes, these foods are reduced or eliminated in the Alpha Nutrition Program.

    We ask a simple question - If there is any possibility that chronic symptoms such as attacks of migraine, heart rhythm abnormalities, digestive disturbances, breathing difficulties or brain dysfunction are linked to food ingestion, would it not be prudent to investigate and remove food -causes using diet revision as an inexpensive, safe, effective strategy?

    Keaney et al reported that:” background Inflammation within vulnerable coronary plaques may cause unstable angina by promoting rupture and erosion. In unstable angina, activated leukocytes may be found in peripheral and coronary-sinus blood. “

    A non-specific indicator of inflammation is the C-reactive protein levels in the blood. Elevated levels are associated with increased risk of heart attacks and strokes. For example, Ridker et al studied 27,939 apparently healthy American women, who were followed for eight years for the occurrence of myocardial infarction, ischemic stroke, coronary revascularization, or death from cardiovascular causes. Elevated C-reactive protein levels were a better predictor of vascular events than low LDL cholesterol levels. The researchers reported that: ” 77 percent of all events occurred among women with LDL cholesterol levels below 160 mg per deciliter (4.14 mmol per liter), and 46 percent occurred among those with LDL cholesterol levels below 130 mg per deciliter (3.36 mmol per liter)… C-reactive protein and LDL cholesterol measurements tended to identify different high-risk groups, screening for both biologic markers provided better prognostic information than screening for either alone.”

    Myeloperoxidase is another serum marker of inflammation that may be Myeloperoxidase is an enzyme that generates reactive oxygen species, is released from white blood cells. In one study, plasma myeloperoxidase levels were predictive of subsequent coronary events in patients with chest pain. Myeloperoxidase levels, in contrast to troponin T, creatine kinase MB isoform, and C-reactive protein levels, identified patients at risk for cardiac events in the absence of myocardial necrosis.“

    Inflammation can be treated by removing the causes of inflammation, treating infection and using anti-inflammatory medication such as ASA. The role of food proteins and immune complexes as agents of inflammation is rarely investigated and may turn out to be the hidden agent behind many heart attacks and strokes.

    Inflammation and Food Proteins

    Other food-related problems, especially immune responses to food proteins (food allergies) may be important contributors. The Pritikin diet and other low-fat diets may not work because of the high content of allergenic proteins in cereal grains, skim milk, and egg white. Skim milk is as allergenic as whole milk. Egg white is the allergenic protein avoided on hypoallergenic diets, but it may be permitted on low cholesterol diets. Protein antigens, arriving in the blood through GIT, may trigger an immune response that inflames and damages the arterial wall. Many people with delayed pattern food allergy develop migraine, angina, heart rhythm abnormalities and may be more likely to develop blood clots and inflammation of blood vessel walls, all features of the life-threatening complex of vascular disease.

    Dr. William Hollander of Boston University suggested that atherosclerosis was an autoimmune disorder with immune complexes injuring blood vessel walls. We think that circulating immune complexes often contain food proteins as antigens and this mechanism is important in causing a wide spectrum of food allergic disease. Since proteins derived from meat, milk, eggs and wheat have the highest risk of appearing in the blood as immune complexes, these foods are reduced or eliminated in the Alpha Nutrition Program.

    We ask the question: If there is any possibility that chronic symptoms such as attacks of migraine, heart rhythm abnormalities, digestive disturbances, breathing difficulties or brain dysfunction are linked to food ingestion, would it not be prudent to investigate and remove food-causes using diet revision as an inexpensive, safe, effective strategy?


    Keaney, J. F. Jr., Vita, J. A. (2002). The Value of Inflammation for Predicting Unstable Angina. N Engl J Med 347: 55-57

    Paul M. Ridker, M.D., Nader Rifai, Ph.D., Lynda Rose, M.S., Julie E. Buring, Sc.D., and Nancy R. Cook, Sc.D. Comparison of C-Reactive Protein and Low-Density Lipoprotein Cholesterol Levels in the Prediction of First Cardiovascular Events. NEJM Volume 347:1557-1565 November 14, 2002 Number 20

    Marie-Luise Brennan, Ph.D., Marc S. Penn, M.D., Ph.D., Frederick Van Lente, Ph.D., et al Prognostic Value of Myeloperoxidase in Patients with Chest Pain NEJM Volume 349:1595-1604 October 23, 2003


    • Topics from the book Heart & Arterial Disease The author is Stephen Gislason MD 2018 Edition: 190 Pages

      Major diseases originate from eating too much of the wrong food and damage is done to many organs simultaneously. The evidence does suggest that some interventions are beneficial in terms of preventing heart attacks and strokes and that disease progression can be halted by important changes in diet and increased exercise. The occurrence of a heart attack or stroke confirms that atherosclerosis is advanced, damage has been done and that the rules of intervention have changed. We suggest that a prudent person suffering early vascular dysfunction symptoms would be wise to pursue vigorous, thorough diet revision at the earliest opportunity.

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